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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f580017b1aded6d839cdff63f71db8d07434987d6dfec953144ca56737426014' 
  AND token = 'H9WfgGTWbI9o2xmb7p54/rOH2QRjqh3U+qxqg6dxKg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}