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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de099787ad7a06b29b99d852e75b3a3a716ee1c6f32d80a6445c1c2191a0e09a' 
  AND token = 'oN8bi1YJoOVbu5QSkEWaBIoEpSdzaGGVGMQ2/iIbQ+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}