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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9425d1d05d441b38ca248c8d80ba6ce11cc415cea06a8dd040472ca7855c077a' 
  AND token = '7PjsIo+Jo5i5cMaP/OCDUe+920Y4ZPSVlihkjsv95XA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}