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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f6897a338ff2b663165d4960d95e7d2790c8a4a35cfee96248a66e9e4f1591a' 
  AND token = 'GbO379vAb1yUv/O6M3HxKF4PRX7tdx5UM5dUC3c4Shc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}