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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d33ed7d0dd880565db19332f213c6abf87b67464317fa9f3481c9a3f6ab63ee' 
  AND token = 'HZvt/r6mXi0D3/GCUsrxtVDy9uo/ojpsy7Suz9BIdsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}