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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a5219be17c15255d418c695ae031e5737c056ee939422c66a6c74bdcf6230e1' 
  AND token = '3i/rFLrfFpfIAYKMILeMviPslofAFyCC5eqUHwPJ7YE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}