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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6665350a44452f875b70d60189ed1e0e5b152f2e19d5d37cd541d38ca4e6110c' 
  AND token = 'bbjjKaTn3+PWizKYOyPY41qA4QDoY4Gx+HSC7qny4gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}