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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c88e3b81c92b7caa17070c24b49a2ad4120f26717ee2de89b32dc78e022271c' 
  AND token = 'CA99rt9RhXd07EQ5SQNe9uPHLGdC8QMxNXMcnMM0frc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}