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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74fcdb849055b7c728ae1018a3ddbbe2cdc05be7de2fad3010cacca99ccd37f8' 
  AND token = 'jI9i5BMHkULrqFE6HiC4l8ssXqLxesDmzkz3Ue2IhWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}