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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69f429c78ae33aa7a58f397f952eee99e7481b17be77ce89dde8c8d492512d6b' 
  AND token = '/UCOSXONGitBsIU1hytFshmY80Y0cJ5+hnk2UOi0coA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}