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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5f2ed288fbd6eb87c124a3832d7223e123090dfc154a6740e766494513af44b' 
  AND token = 'axBPO+ji3o72XOwj7IRexHmBIHNLQcrxj9h59EnPwxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}