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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f79bdc5693657d7fd61021009785f18b1558eafbfd9bfb250515d0cd6d5b6fa' 
  AND token = 'HpIvBFBSwCAozoE3Tnuw4VhMK3NRF8gfjNn9EPnQOww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}