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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a00aaae00446bacb556fed9430b6ab26793074f7596bd2d08342c2eb94d9963' 
  AND token = 'W+5dfu40EAsgcAQaxvriDFE53O2v2MV5a6993C3GtDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}