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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3807b38f1e1c7ea03681a7080f2dbb437e6774601c7f73834c39493bee72b7ba' 
  AND token = 'A9PgcFXEaGtuLY5ucP4aNMY9IFAVqxX/V6Kzy5V/89I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}