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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2d3f1e3182686cbfd8585adabca772244d69e0b2203cb5b4e0209950ae2e531' 
  AND token = 'cgx2T0O5Ha6zyIqP1Nj0qhalkTr8+PVTaPVAKa/W13c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}