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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e79c1a5e3ed6e8e169acf9d1439f4767a63cda04bedcdc9dfc4e9e17ff95b0' 
  AND token = 'DEj9ex9O1l3i2yh7wLhoxsntYltTZel+txbKnP3b+6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}