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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '054c635070970a7adfde5344088bb3a5e0c6f3f09bf7cbe1783a31e221f9b1c2' 
  AND token = 'uUZlMoOsI32X9naCGItWSjIKRWgPHJIzLkAN6Yxs8RA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}