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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e28a0e4b84a1140a0ba5b15745c4d9da41b28c0586dbb37280378713c8e3b511' 
  AND token = 't6bKGhVcd8VUgFSgpKYtQ65stK4K8giXt2hHjB2oAOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}