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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a42ebd748140f2d6e03ef2801460b40c8483f147308fd6159ac835a159b7790' 
  AND token = 'UP/rUt4ujRPmjeD2O5ec+Xzfo3fc7rThpWnKnTvmYFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}