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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e1a0caa36960dd3da36cb04a555cc38654d218a8a70bf1323983720468f797' 
  AND token = '3CuhArTe+go71tmPSsj6IRT/7Ias30xWQ8TEaQbNElw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}