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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5a182bc08b1a10959655a33d7c9fff7708b4d8b0da57c1303db12d30c0a8744' 
  AND token = '1O5BsN6oD/2vw8Qo6zuuS0NORytMP+5jZ+tJgkYWEEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}