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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ebf74f3274ad7a0255bcb4b1c0d264dd88c8c8dd6a0de0c50329b907c42003f' 
  AND token = '/Mji+8CVMNw1bu90yDdN+UaBmc433pQfXn9sbnJk4lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}