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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a65120206f2b6362f0e687bec30516591d5a1097c31ac571e11499043ea9ae3' 
  AND token = 'I3+KinEVnrgpiOGDZmr0+bXy2n8T+YmfuGAx8y5huAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}