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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72cf78f76a2e2081f373dce9e8e01395446ec24b3d83addd3cfa0800ecb92adb' 
  AND token = 'PLad5CIHl5tCwMbGmb04jgDrLkwQrmePa65HjT8g+CU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}