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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c168f4dc89775abe53400c33bfc152da7d46e8ec73d51f6b3d41637c3e65b01a' 
  AND token = 'b/fyb1AO5RgWBvuf1zcaE/OXb5rWCL/GbG8pbFdgbWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}