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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1efdbb0fb57895c731594c59e3ea009e205692dbbe057949e0828bcb1aafcae3' 
  AND token = '7N7a0FAItA8qn/OtgxQWCiGs58DQsO7cvHrHWwy6j9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}