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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '224c6b411c58235121ed4a82bcbc1f52c531bad76bf47aecaf9b0f596a7352d8' 
  AND token = '7cwPzGohKk6tTTkD8yrqsB2jZuPR478PUaHHjwPa3aI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}