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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '851ce9e35f5855183df50421cbbf66c565ba959c9ef9f34d03776eb41148c393' 
  AND token = '+kYdHQ195J52dnPhbuTHgLCA0XhpEiSYBFhh0qrJTOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}