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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7d20f384198bb094391a3524f12a852fb40c40ef13fcdfa8aec5a37010a98ed' 
  AND token = 'wPFThP5JZ8xFuAAK8dtvAYtQdKjxRgmDxMf+nRzdW6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}