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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e482c5bd1e459f9f1c87fd078668db063cdcdd0e61c6d7daede8dd449e62d1fe' 
  AND token = 'R8cIgp/Dmiv0Ennc+DcotQZ4mpi07ZZgUCrZ2ZPmC8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}