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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e00db49f76499392695f188fdbb7544211e82da8b00d68a53a4eedd286e8cb' 
  AND token = 'kLhrpuyI/bcBdMMdiv7BqP1Wv7ccYyQvkt/23lDx33k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}