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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c4df851c5422feade48866b8de8dc3efa9d6d34fc6b9e5637468104bfdd20c4' 
  AND token = 'fs9SHOUecJuBmMLdkfST762NLWrjf2g5CKDr7fa9HkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}