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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d3e4e9f612dba83ee987a12c031d1448c3a74e6612786b7ad14de507002188f' 
  AND token = '8xTVgnHZw9tWnj+z/dNYZgK/QIerCFKHIAIY2ZIti3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}