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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b53248229b65f7dee674309b1073bf548e589cf598ff9332120f874f3a0c3f5' 
  AND token = 'nKojO5ffxu1k0IKfnXKD1S8+8rLTDXhUq7NYvgh8P7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}