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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1500254c7d0e884f858dd0eb3defdb25dba71c5a6af43baa341adf3bfae06d59' 
  AND token = '8CKE4EDqlWOu0htg7UzS/gLRm9liF5MJDN8Z88Xw5w0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}