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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c46bdd598b832f340d69e4ef07c010cb8eaf6305fa9af46d75c009a1f70ed109' 
  AND token = 'iIxlE4DtYTm1rBMxdOtjBZsXzfx6W5BrjXw1NdWkbkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}