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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bc9761c45b08f475e8fe799a63d2a1f06f03aa1db54874a0035640a1ffec466' 
  AND token = '6gETcrTVSXkXH+zRVzy33i6EdqzC4oy0psEgxRZnrCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}