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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac78611155a443637a7504674940a40b572fff8af130c9489880f8d5999e2b18' 
  AND token = '8zB21IKNtspQCNYkzyM9wMQL/ei+rHeGtYmZot32QmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}