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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee18d21ff16a61008298fef248930ab1441050908b518a9c49c1a70f11ac7a48' 
  AND token = 'HReqDE35C5QhZQPnMbIPY4WcV/7bca9xUN474cFkb4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}