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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4736ffb4a6b035d04e8b7b30941ba503b99d0fcfe1806ed7bbb004885994ac6e' 
  AND token = '2SAENZb1XppeFjB/Sjb/eVp0heBtG5QmgC7q10vSmRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}