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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65a478263854239c15cbd2d55a330dcfbfc5c296f4224a7d843785eb58c1ece9' 
  AND token = 'A55ftJgfUCpKpvsxxWi8C3tANmnU7LA8KQt5e9Nbdfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}