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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a2074bdd2641c412d997366416290f06e3c28e3e37921fbbb6a0cdbe3816fea' 
  AND token = 'aa51J0kYVlHL8FBSBBHvZB+c3lTOo5PkmZPO/TZPahc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}