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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '743d75806690496a19f1cbf1b7f8d65cfcf69b81da314b38c22bc752a1b924b6' 
  AND token = 'pExpxhIiDO8cJO68q+MZ93YnUC1c7kcZr29kl+lNKOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}