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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c61ec88056883abdc9c51534c6f9a4b63ca71a36bb6c478b440004109c3ce02' 
  AND token = '7KBQNCN8mm9k+nfD+TnCVA2R3QjGEGeErpa1xlY2xCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}