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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a2ab79fbcee2b076a08aea18bfc657908928eb16f3e8191f1809111b56b7f9' 
  AND token = 'mTO8haV7XTs7jC4qMT5UT+JPOIwhTrGBWmY6OHXslPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}