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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f62f00db84c1a14575e1cfc8e2c706f1ac20de2c0cedaeaa949a991c78da6270' 
  AND token = 'gIgmeYOUfEodZ4U3q9a0KrdmX9L3z9V9doPG7ZsmzPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}