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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d9361b5fdc015a507251529d76c17d775436e114b275b7a97707284f98f56b' 
  AND token = 'jPCIywyUTCHgwo0dVf+y6v/o+OHFFtIxDpSwMln6o00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}