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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6139f78c3a4a8fb2ce50bcb49b207c13c6455a296d74a8332d045113315d8d35' 
  AND token = '2qbvzZRW1Lvxs7TbuP3jRg3Roj9sTxNEMmjjoM2OIwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}