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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0949348582478661cf248231f0e1499f853deff77e7e4c6ca0c4f402dabb9630' 
  AND token = 'bbRQ1o+JoYhRmf23UEebnUp5EQIOM/v7gfMV9H7bkjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}