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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aef724caa4a5f701571f8d55eb80af488e1afdaf435043ace7fb441020eff03' 
  AND token = '+n9tE6OBENMM61tSMeXpI3EoVfxeSNHRrmYzkcr0/VE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}